After Hours Keeps Clock Researchers CRYing Overtime
نویسندگان
چکیده
Three recent reports, including one in this issue of Cell, reveal that the circadian regulator CRY is targeted for degradation by the F box E3 ubiquitin ligase FBXL3 (Siepka et al., 2007; Busino et al., 2007; Godinho et al., 2007). These studies confirm the importance of targeted protein degradation as a key design feature of the mammalian circadian clock.
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ورودعنوان ژورنال:
- Cell
دوره 129 شماره
صفحات -
تاریخ انتشار 2007